PROLONGED NEUROMUSCULAR BLOCKADE
نویسندگان
چکیده
منابع مشابه
Prolonged vecuronium neuromuscular blockade associated with Charcot Marie Tooth neuropathy.
Charcot Marie Tooth (CMT) disease comprises a group of disorders characterized by progressive distal muscle weakness and wasting. Review of the anaesthetic literature produced conflicting reports concerning the responses to neuromuscular blocking drugs in these patients. We describe a case in which vecuronium 0.11 mg kg(-1) produced prolonged neuromuscular blockade lasting 115 min in a patient ...
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Neuromuscular blocking agents (NMBAs) have been widely used to control patients who need to be immobilized for some kind of medical intervention, such as an invasive procedure or synchronism with mechanical ventilation. The purpose of this monograph is to review the pharmacology of the NMBAs, to compare the main differences between the neuromuscular junction in neonates, infants, toddlers and a...
متن کاملMonitoring neuromuscular blockade.
Neuromuscular-blocking agents (NMBA) have been used in clinical anesthesia for nearly 60 years. In the perioperative period, a variety of factors can influence a patient’s response to these drugs. To precisely titrate NMBAs to clinical effects in the anesthetized patient, the application of neuromuscular monitoring is essential. The use of a peripheral nerve stimulator allows the clinician to a...
متن کاملComparison of large dose of vecuronium with pancuronium for prolonged neuromuscular blockade.
Dose-duration relationships for vecuronium were determined and the duration of action produced by vecuronium 0.3 mg kg-1 shown to equal that of pancuronium 0.1 mg kg-1. Using these doses, the neuromuscular blocking properties and cardiovascular effects of the two drugs were compared. With large dose administration of vecuronium (0.3 mg kg-1), both the onset time (mean 81 s) and the 25-75% recov...
متن کاملSugammadex rescue following prolonged rocuronium neuromuscular blockade with 'recurarisation' in a patient with severe renal failure.
We describe our experience of a 71-year-old patient with severe renal failure, who exhibited an unusually prolonged rocuronium-induced neuromuscular blockade (>4 h) and apparent recurarisation, following emergency rapid sequence induction (RSI). At the end of operation, 45 min post induction, train-of-four (TOF) testing had been 4/4 prior to wake up. No respiratory effort was seen 150 min posti...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1973
ISSN: 0007-0912
DOI: 10.1093/bja/45.4.380-c